Risk of New-Onset Atrial Fibrillation and Stroke after Radiofrequency Ablation of Isolated Typical Atrial Flutter

Heart Rhythm journal: July 01, 2014 Background Radiofrequency ablation (RFA) is considered a curative procedure for typical atrial flutter (AFL), however, patients remain at risk for developing new atrial fibrillation (AF). Objective We sought to determine the incidence and predictors of new-onset AF and stroke after RFA of isolated AFL in a multicenter cohort. Read More

Prognostic Value of Atrial Fibrillation Inducibility Following Right Atrial Flutter Ablation

Heartrhythmjournal: June 27, 2014 Background Patients with typical right atrial flutter (AFL) may also have underlying atrial fibrillation (AF) or be at high risk of developing AF. Inducibility of AF among patients undergoing AFL ablation may be an important predictor of future occurrence of AF and may be useful in guiding management of this patient population. […]

Digoxin in patients with permanent atrial fibrillation: Data from the RACE II study

Heartrhythmjournal:  June 10, 2014 The Atrial Fibrillation Follow-up Investigation of Rhythm Management trial showed that digoxin was associated with increased mortality in patients with atrial fibrillation. Objectives To assess the association of digoxin with cardiovascular (CV) morbidity and mortality in patients with permanent atrial fibrillation enrolled in the Dutch Rate Control Efficacy in Permanent AF: […]

Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation

Neurology February 25, 2014 Objective: To update the 1998 American Academy of Neurology practice parameter on stroke prevention in nonvalvular atrial fibrillation (NVAF). How often do various technologies identify previously undetected NVAF? Which therapies reduce ischemic stroke risk with the least risk of hemorrhage, including intracranial hemorrhage? The complete guideline on which this summary is based is […]

New Drugs and Technologies: Left Atrial Appendage Closure to Prevent Stroke in Patients With Atrial Fibrillation

CIRCULATIONAHA: 7/8/14 trial fibrillation (AF) is the most common sustained arrhythmia and is associated with substantial morbidity. The prevalence of AF in the United States is expected to rise to between 5.6 and 12 million in 2050.1 AF is associated with a 4- to 5-fold increased risk of ischemic stroke after adjustment for other risk factors,2 and paroxysmal, […]

New oral anticoagulants in patients with atrial fibrillation

The Lancet: July 5, 2014 From a meta-analysis of four studies, Christian Ruff and colleagues1 concluded that use of new oral anticoagulants (NOACs) in patients with atrial fibrillation results in a decreased incidence of stroke and mortality when compared with warfarin. However, the mean time in therapeutic range (TTR) was less than 65% in the warfarin group […]

Intracranial Hemorrhage Mortality in Atrial Fibrillation Patients Treated With Dabigatran or Warfarin

STROKEAHA: July 3, 2014 Background and Purpose—In randomized trials, patients with atrial fibrillation (AF) receiving dabigatran, a direct oral anticoagulant, had lower risk of intracranial bleeding (ICB) than those on warfarin. However, concerns exist about potential worse outcomes in dabigatran users if bleeding occurs, given the lack of approved reversal agents. Thus, we examined in-hospital mortality […]

Healthcare Utilization and Clinical Outcomes after Catheter Ablation of Atrial Flutter

PLOS: July 01, 2014 Atrial flutter ablation is associated with a high rate of acute procedural success and symptom improvement. The relationship between ablation and other clinical outcomes has been limited to small studies primarily conducted at academic centers. We sought to determine if catheter ablation of atrial flutter is associated with reductions in healthcare […]

Atrial Fibrillation in Patients with Cryptogenic Stroke

NEJM: June 26, 2014 BACKGROUND Atrial fibrillation is a leading preventable cause of recurrent stroke for which early detection and treatment are critical. However, paroxysmal atrial fibrillation is often asymptomatic and likely to go undetected and untreated in the routine care of patients with ischemic stroke or transient ischemic attack (TIA). METHODS We randomly assigned […]

Cryptogenic Stroke and Underlying Atrial Fibrillation

NEJM: June 26, 2014 BACKGROUND Current guidelines recommend at least 24 hours of electrocardiographic (ECG) monitoring after an ischemic stroke to rule out atrial fibrillation. However, the most effective duration and type of monitoring have not been established, and the cause of ischemic stroke remains uncertain despite a complete diagnostic evaluation in 20 to 40% […]

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