Successful Catheter Ablation Decreases Platelet Activation and Improves Endothelial Function in Patients with Atrial Fibrillation

Heartrhythmjournal: July 25, 2014 Background Nonvalvular atrial fibrillation (AF) confers a five-fold increased risk of stroke. Whether catheter ablation (CA) subsequently decreases prothrombotic risk is unknown. Objective We sought to assess the long-term effects of CA for AF on prothrombotic risk. Methods Fifty-seven patients undergoing CA for AF were prospectively studied. Platelet activation (CD62P [platelet P-selectin] […]

Stroke Prevention in Patients With Atrial Fibrillation and Renal Dysfunction

STROKEAHA: June 26, 2014 The overall prevalence of atrial fibrillation (AF) is 1% of the US population. However, diagnosis of AF is increasingly common with age, and prevalence rises to ≈10% in Americans aged >80 years. As the population ages, the estimated prevalence of AF may nearly triple from 2.3 million to 5.6 million US adults […]

Left Atria Strain Is a Surrogate Marker for Detection of Atrial Fibrillation in Cryptogenic Strokes

STROKEAHA:  June 26, 2014 After complete diagnostic workup, a quarter of ischemic strokes are regarded as undetermined pathogenesis at discharge with a substantial rate of mortality in some cases.1 Paroxysmal atrial fibrillation (PAF) is the most frequent occult cause resulting in significant morbidity and costs when is under diagnosed.2 Recent studies have shown that extending the cardiac monitoring […]

Characteristics affecting oral anticoagulant therapy choice among patients with non-valvular atrial fibrillation: a retrospective claims analysis

BMC Health Services Research 2014 Background Dabigatran is one of the three newer oral anticoagulants (OACs) recently approved in the United States for stroke prevention in non-valvular atrial fibrillation (NVAF) patients. The objective of this study was to identify patient, healthcare provider, and health plan factors associated with dabigatran versus warfarin use among NVAF patients. Methods […]

Peripheral pulse measurement after ischemic stroke

Neurology: July 23, 2014 Objective: To investigate feasibility and diagnostic accuracy of measurement of the peripheral pulse (MPP) at the radial artery as a simple, noninvasive screening tool for paroxysmal atrial fibrillation (pAF) in patients after acute ischemic stroke. Methods: Two hundred fifty-six patients with acute ischemic stroke and the patients’ relatives at a tertiary stroke center were […]

Atrial Fibrillation and Cognitive Decline−The Role of Subclinical Cerebral Infarcts

STROKEAHA: July 22, 2014 Background and Purpose—The mechanism underlying the association of atrial fibrillation (AF) with cognitive decline in stroke-free individuals is unclear. We examined the association of incident AF with cognitive decline in stroke-free individuals, stratified by subclinical cerebral infarcts (SCIs) on brain MRI scans. Read more

Arrhythmia and Electrophysiology

J Am Heart Assoc.: July 2014 Improvement in Quality of Life After Catheter Ablation for Paroxysmal Versus Long‐standing Persistent Atrial Fibrillation: A Prospective Study With 3‐Year Follow‐up Background Changes in quality of life (QoL) after catheter ablation for long‐standing persistent atrial fibrillation (LSPAF) are not well described. We sought to compare QoL improvement after catheter ablation of […]

High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke

STROKEAHA:  July 17, 2014 Background and Purpose—Atrial fibrillation (AF) is a common cause of devastating but potentially preventable stroke. Estimates of the prevalence of AF among patients with stroke vary considerably because of difficulties in detection of intermittent, silent AF. Better recognition of AF in this patient group may help to identify and offer protection to […]

Risk Predictors of Stroke and Mortality Following Ablation For Atrial Fibrillation: the California experience 2005-2009

Heart Rhythm Journal: July 15, 2014 Background Ablation (ABL) is a second line therapy for the management of atrial fibrillation (AF). Single center studies have demonstrated the safety and efficacy of ABL, however the low event rates render it difficult to assess predictors of major adverse events. Objectives To determine the population-based incidence of data and […]

Mapping of Focal Atrial Tachycardia with an Un-Interpretable Activation Map Following Extensive Atrial Ablation: Tricks and Tips

AHA- CIRCEP.: July 13, 2014 Background—Atrial tachycardias (ATs) following extensive ablation are increasingly common and challenging arrhythmias. The prolonged intra-atrial conduction time (IACT) during ATs in the milieu may complicate the mapping of focal ATs. The present study characterized the electrophysiological features of ATs in this unique setting and to further delineate an effective mapping strategy. […]

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