Cannabis, Ischemic Stroke, and Transient Ischemic Attack

STROKEAHA: May 21, 2013 Background and Purpose—There is a temporal relationship between cannabis use and stroke in case series and population-based studies. Methods—Consecutive stroke patients, aged 18 to 55 years, who had urine screens for cannabis were compared with a cohort of control patients admitted to hospital without cardiovascular or neurological diagnoses. Results—One hundred sixty of […]

Trials of endovascular therapies or collaterals?

International Journal of Stroke: May 20, 2013 Several landmark clinical trials of endovascular therapy for acute ischemic stroke have recently jolted the concerted multidisciplinary efforts to develop effective revascularization strategies. Further consideration of these four endovascular stroke trials published in the last year suggests a more fundamental question: are these trials of specific treatments or […]

Assessing the impact of dabigatran and warfarin on health-related quality of life: Results from an RE-LY sub-study

International Journal of Cardiology:  May 10, 2013 Background Anticoagulation is recommended in patients with atrial fibrillation (AF) to prevent strokes. Vitamin K antagonists, such as warfarin, are associated with numerous practical limitations – frequent anticoagulation monitoring, lifestyle and dietary restrictions – that complicate patient management and may impact health-related quality of life (HRQoL). This study […]

Fish Oil and Post-Operative Atrial Fibrillation

JACC: May 28, 2013 Post-operative atrial fibrillation (PoAF) is among the most common complications of cardiac surgery and substantially increases morbidity and healthcare costs. Despite decades of surgical, anesthetic, and medical advances, rates of PoAF remain largely unchanged. Experiments and animal models suggest that perioperative fish oil (omega-3 fatty acids) may reduce PoAF (1). We […]

Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials

International Journal of Stroke: May 22, 2013 Background It remains controversial whether dual antiplatelet therapy reduces stroke more than aspirin alone. Aim We aimed to assess the effects of adding clopidogrel to aspirin on the occurrence of stroke and major haemorrhage in patients with vascular disease. Methods Meta-analysis of published randomized trials comparing the combination […]

Cannabis, Ischemic Stroke, and Transient Ischemic Attack

STROKEAHA: May 21, 2013 Background and Purpose—There is a temporal relationship between cannabis use and stroke in case series and population-based studies. Methods—Consecutive stroke patients, aged 18 to 55 years, who had urine screens for cannabis were compared with a cohort of control patients admitted to hospital without cardiovascular or neurological diagnoses. Read more

Trials of endovascular therapies or collaterals?

International Journal of Stroke: May 20, 2013 Several landmark clinical trials of endovascular therapy for acute ischemic stroke have recently jolted the concerted multidisciplinary efforts to develop effective revascularization strategies. Further consideration of these four endovascular stroke trials published in the last year suggests a more fundamental question: are these trials of specific treatments or […]

Assessing the impact of dabigatran and warfarin on health-related quality of life: Results from an RE-LY sub-study

International Journal of Cardiology: May 10, 2013 Background Anticoagulation is recommended in patients with atrial fibrillation (AF) to prevent strokes. Vitamin K antagonists, such as warfarin, are associated with numerous practical limitations – frequent anticoagulation monitoring, lifestyle and dietary restrictions – that complicate patient management and may impact health-related quality of life (HRQoL). This study […]

nsertable Cardiac Event Recorder in Detection of Atrial Fibrillation After Cryptogenic Stroke

STROKEAHA: May 14, 2013 Background and Purpose—Atrial fibrillation (AF) is the most frequent risk factor in ischemic stroke but often remains undetected. We analyzed the value of insertable cardiac event recorder in detection of AF in a 1-year cohort of patients with cryptogenic ischemic stroke.   Read more

Immunohistochemical Analysis of Thrombi Retrieved During Treatment of Acute Ischemic Stroke

STROKEAHA: May 14, 2013 Background and Purpose—To provide evidence whether mechanical thrombectomy with stent-retrievers in the treatment of acute ischemic stroke causes intimal damage. Methods—This study analyzed thrombi retrieved by mechanical thrombectomy from cerebral arteries in 48 consecutive patients with acute ischemic stroke for the presence of endothelial cells using CD34 antibodies. Read more

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