Atrial Fibrillation
Thursday, October 25th, 2012
The American Journal of Medicine: November 1, 2012 Atrial fibrillation is common among patients with cardiovascular disease and is a frequent complication of the acute coronary syndrome. Data are needed on recent trends in the magnitude, clinical features, treatment, and prognostic impact of preexisting and new-onset atrial fibrillation in patients hospitalized with an acute coronary […]
Atrial Fibrillation
Thursday, October 25th, 2012
Stop AFIB: October 24, 2012 Brussels, Belgium — October 24, 2012 — Ahead of World Stroke Day 2012 (October 29), European Policy Makers have joined over 90 Medical and Patient Organisations, and more than 100,000 people, in supporting the Global Atrial Fibrillation (AF) Patient Charter and calling for National Governments and the World Health Organisation to act to make the […]
Atrial Fibrillation
Thursday, October 25th, 2012
JAMA Network: October 22, 2012 The major challenges of warfarin therapy relate to poor adherence and persistence, the need for regular monitoring, and the risk of hemorrhage. In clinical trials, persistence with warfarin treatment ranges from 75% to 79% at 1 year,1– 2 but persistence in clinical practice is thought to be poorer. Small observational studies suggest […]
Atrial Fibrillation
Thursday, October 25th, 2012
Journal of Cardiovascular Disease Research: October 19, 2012 Atrial fibrillation (AF) is recognized as the most common cardiac arrhythmia, accounting for a lifetime risk of about 25%. [1],[2],[3] It presents a 5-6 fold increased stroke risk and accounts for at least one in every seven ischemic strokes. The common conception is that highest risk of embolic stroke is […]
Atrial Fibrillation
Thursday, October 25th, 2012
Biomedcentral: 10/18/12 There is limited information about any association between the onset of atrial fibrillation (AF) and the presence of valvular disease. Methods We retrospectively examined 940 patients in sinus rhythm, examined by echocardiography in 1996. During 11 years of follow-up, we assessed the incidence of AF and outcome defined as valvular surgery or death, in […]
Clinical Trials
Thursday, October 25th, 2012
Stroke AHA Journals: November 1, 2012 Recent analysis of National Get-with-the-Guidelines data has shown that less than one third of all patients treated with intravenous tissue plasminogen activator (tPA) had door-to-needle times (DTN) within the ‘Golden Hour’ recommended by current guidelines. Accumulating evidence indicates that shorter DTN is associated with improved outcomes. In March 2011, […]
Clinical Trials
Thursday, October 25th, 2012
The New England Journal of Medicine (NEJM): October 25, 2012 There are limited data comparing radiofrequency catheter ablation with antiarrhythmic drug therapy as first-line treatment in patients with paroxysmal atrial fibrillation. METHODS We randomly assigned 294 patients with paroxysmal atrial fibrillation and no history of antiarrhythmic drug use to an initial treatment strategy of either radiofrequency catheter […]
Clinical Trials
Thursday, October 25th, 2012
Wiley: OCT 23, 2012 The cluster-randomized controlled trial is a design increasingly used in prevention and health care evaluation studies and is highly relevant to stroke research. However, there are methodological issues that make it complex to implement. These are not always fully appreciated, with reviews continuing to reveal deficiencies. We searched PUBMED and CENTRAL databases […]
Clinical Trials
Thursday, October 25th, 2012
Stroke AHA Journals: October 23, 2012 With Recent Transient Ischemic Attack or Stroke Elevated concentrations of homocysteine are associated with cerebral small vessel disease (CSVD). B-vitamin supplementation with folate and vitamins B12and B6 reduces homocysteine concentrations. In a substudy of the VITAmins TO Prevent Stroke (VITATOPS) trial, we assessed the hypothesis that the addition of once-daily supplements […]
Clinical Trials
Thursday, October 25th, 2012
NIH: October 19, 2012 Intervention stopped early in NIH-funded study of weight loss in overweight and obese adults with type 2 diabetes after finding no harm, but no cardiovascular benefits An intensive diet and exercise program resulting in weight loss does not reduce cardiovascular events such as heart attack and stroke in people with longstanding […]