Defining Clinically Relevant Cerebral Hemorrhage After Thrombolytic Therapy for Stroke

STROKEAHA: August 5, 2014 Analysis of the National Institute of Neurological Disorders and Stroke Tissue-Type Plasminogen Activator Trials Background and Purpose—Several definitions have been proposed to distinguish clinically relevant from incidental cerebral hemorrhagic transformation after thrombolytic therapy for acute ischemic stroke. We investigated which definition best identifies cerebral hemorrhages that alter long-term functional outcome in the […]

Variation in Restarting Antithrombotic Drugs at Hospital Discharge After Intracerebral Hemorrhage

AHA: July 31, 2014 Background and Purpose—Whether intracerebral hemorrhage (ICH) survivors should restart antithrombotic drugs is unknown. We analyzed the frequency of restarting antithrombotic drugs in ICH survivors who had taken prophylactic antithrombotic drugs in atrial fibrillation or after thromboembolic disease in 5 cohorts and explored factors associated with doing so. Methods—We compared the characteristics […]

Reducing the Risk of Heart Attack and Stroke

Ischemic Stroke

CIRCULATIONAHA: 8/5/14 The American Heart Association/American College of Cardiology Prevention Guidelines A 58-year-old man, JB, schedules a visit with his primary care physician to explore what he could do to prevent a heart attack or stroke. He previously considered himself in good health and is not aware of any medical problems or symptoms. His visit is […]

The Evolution and Future of ACC/AHA Clinical Practice Guidelines: A 30-Year Journey

JACC: August 2014 A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Read more

Association of baseline dyslipidemia with stroke recurrence within five-years after ischemic stroke

brain2

Wiley: 8/4/14 Background and purpose The association between dyslipidemia (DL) and stroke recurrence is unclear, but may be influenced by different subtypes of stroke. This study aims to explore whether DL contributes to the recurrence of certain subtypes of ischemic stroke. Methods Data from the Ege Stroke Registry was examined, and five-years follow-up data for […]

Outcome in patients admitted outside regular hospital working hours: Does time until regular working hours matter?

hosptial7

Wiley: 8/4/14 Aims The aim of this study was to investigate whether stratifying patients according to the time period from admission to the start of regular working hours would help detect a weekend effect in acute stroke patients. Methods Ischemic stroke patients admitted between October 2002 and March 2012 were analyzed. Working hours were defined […]

Prevalence of Coronary Heart Disease or Stroke Among Workers Aged <55 Years — United States, 2008–2012

CDC: August 1, 2014 Cardiovascular disease accounts for one in three deaths in the United States each year, and coronary heart disease and stroke account for most of those deaths (1). To try to prevent 1 million heart attacks and strokes by 2017, the U.S. Department of Health and Human Services launched the Million Hearts […]

Systolic Blood Pressure Levels Among Adults With Hypertension and Incident Cardiovascular Events

JAMA: August 2014 Importance  Studies document a progressive increase in heart disease risk as systolic blood pressure (SBP) rises above 115 mm Hg, but it is unknown whether an SBP lower than 120 mm Hg among adults with hypertension (HTN) lowers heart failure, stroke, and myocardial infarction risk. Objective  To examine the risk of incident cardiovascular (CV) […]

Early Cerebral Thromboembolic Complications following Radiofrequency Catheter Ablation of Atrial Fibrillation: Incidence, Characteristics and Risk Factors

Heart rhythm journal: July 30, 2014 Background Thromboembolic complications remain one of the most severe adverse events associated with catheter ablation of atrial fibrillation (AF) but there are limited data on those events. Objective The aim of this study was to evaluate the incidence, characteristics and risk factors of thromboembolic complications after AF ablation. Methods Cerebral […]

A Common SCN5A Variant is Associated with PR Interval and Atrial Fibrillation among African Americans

Wiley: 7/28/14 Abstract Objective We examined the association of rs7626962 (S1103Y) or rs7629265, a variant in high linkage disequilibrium with S1103Y (r2 = 0.87–1), with sudden cardiac death (SCD) and atrial fibrillation (AF) among African Americans. Background The SCN5A missense variant S1103Y has been associated with SCD among African Americans in small case-control studies, but larger population-based studies are […]

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